High theophylline levels

Author: zvoc

August undefined, 2024

WebMar 1, 2024 · At serum Theophylline concentrations > 20 mcg/mL, both the frequency and severity of adverse reactions increase. In general, maintaining peak serum Theophylline concentrations between 10 mcg/mL and 15 …

PMY 420 ASSIGNMENT 10 - 2008.doc - PMY 420 - Course Hero

WebToxic side effects of elevated theophylline levels range from minor symptoms to life-threatening complications. We investigated the incidence of life-threatening events in … WebJul 11, 2024 · Theophylline levels: Serum theophylline levels should be monitored after initiation of therapy, prior to making dose increases; in the presence of signs or symptoms of toxicity; ... • High blood sugar like confusion, fatigue, increased thirst, increased hunger, passing a lot of urine, flushing, fast breathing, or breath that smells like fruit ... dunchurch road

Theophylline - StatPearls - NCBI Bookshelf

WebSerum theophylline levels were measured in 23 consecutive asthmatics presenting to the ER in an acute attack. 15 (68%) had therapeutic levels (above 10 mcg/ml) and 2 had toxic levels (above 20 mcg/ml), prior to receiving the standard … WebNo food or liquid (other than water) was allowed for 4 hours after which a standard lunch was served. Mean peak theophylline serum levels (C max) was 6.69 mcg/mL and mean … WebB. Estimate Mr B’s theophylline level at the time of fitting C. How long after stopping Nuelin will Mr B’s theophylline be within the therapeutic range? [Population data: clearance = 0.04 L/hr/kg & volume of distribution = 0.48 L/kg. CHF reduces theophylline clearance by 50%. F … dunchurch school junior

Theophylline (Oral Route) Side Effects - Mayo Clinic

WebHigh blood theophylline levels can lead to symptoms of toxicity (see below). Therefore, theophylline blood levels are monitored periodically during treatment to assure achievement of optimal and safe levels. The initial dose is 300-600 mg once daily or as a divided dose for 3 days. The maintenance dose is 400-600 mg daily. WebThe adverse effects of theophylline include: Gastrointestinal disorders such as nausea, vomiting, gastro-oesophageal reflux. Neurological disorders such as tremor, headache, dizziness, central nervous system stimulation, insomnia, and convulsion (rare). Psychiatric disorders such as anxiety. dunchurch railway stationWebMar 18, 2010 · Theophylline (3-methyxanthine) has been used to treat airway diseases for over 70 years. It was originally used as a bronchodilator but the relatively high doses required are associated with frequent side effects, so its use declined as inhaled β2-agonists became more widely used. dunchurch school holidays

"WebTHEOPHYLLINE AS A BRONCHODILATOR. Traditionally, theophylline was used as a bronchodilator in the treatment of airway disease but, to achieve significant bronchodilatation comparable with that of a β 2 agonist, relatively high plasma concentrations are needed (10–20 mg/l). Theophylline relaxes human airway smooth … " - High theophylline levels

High theophylline levels

Aminophylline - StatPearls - NCBI Bookshelf

WebJun 20, 2024 · High blood sugar (increased thirst, increased urination, hunger, dry mouth, drowsiness, blurred vision, weight loss) ... Low levels of theophylline and caffeine may indicate that the drug has not reached a therapeutic level for the individual tested and there is insufficient drug present to be effective. WebTheophylline interacts with many drugs including: Beta-2 agonists, corticosteroids, diuretics — potentially serious hypokalaemia may result from beta-2 agonist therapy. Check serum …

Did you know?

WebAug 31, 2024 · High-risk cases include the following: Acute overdose with theophylline levels higher than 80 mcg/mL Chronic toxicity with levels higher than 40 mcg/mL Patients … WebMar 22, 2024 · Theophylline: Although causality has not been established, concurrent use of pentoxifylline with theophylline has resulted in elevated theophylline plasma levels, which may enhance the possibility of adverse effects. Drug-Food Interactions. Interactions with food have not been established. Drug-Herb Interactions

WebFactor which increase the half life include heart failure, cirrhosis, viral infection and drugs like cimetidine, ciprofloxacin, erythromycin and the oral contraceptive pill. The half life is decreased by smoking, heavy drinking and drugs like phenytoin, carbamazepine, rifampicin and barbiturates. WebSixty patients with theophylline toxicity were hospitalized during a 2-year period. Eleven patients had hypercalcemia; their calcium levels returned to normal as theophylline levels …

WebTheophylline levels may be modestly altered in thyroid dysfunction. In hyperthyroidism, theophylline metabolism is increased, and therefore the dose may need to be reduced as thyroid levels are corrected. Conversely, patients with hypothyroidism may need the dose of theophylline increased as treatment with levothyroxine or liothyronine continues. WebJun 30, 2024 · Adults are may be given about 300-600mg of Theophylline per day depending on their condition. This amount is equivalent to the therapeutic dose which is between 10-20mg/L. If the amount of 25mg/L, it …

WebToo much theophylline can be life-threatening. Symptoms of too much theophylline include: Vomiting, heartburn, and belly pain. Rapid heart rate or other changes in heart rhythm. …

WebJan 14, 2024 · Check with your doctor immediately if any of the following side effects occur while taking theophylline: Incidence not known Chest pain or discomfort dizziness fainting fast, slow, or irregular heartbeat increase in urine volume lightheadedness persistent vomiting pounding or rapid pulse seizures shakiness dunchurch rugby mapWebSafe levels for people taking theophylline are often 8 to 20 mcg/mL. Levels above 20 mcg/mL may be harmful and can happen if people take too many pills within a short time … dunchurch servicesWebTheophylline in overdose can cause vomiting (which may be severe and intractable), agitation, restlessness, dilated pupils, sinus tachycardia, and hyperglycaemia. More … dunchurch secure storageWebSafe levels for people taking theophylline are often 8 to 20 mcg/mL. Levels above 20 mcg/mL may be harmful and can happen if people take too many pills within a short time period. Such cases might include accidentally taking extra pills or having a prescription that was written for too high a dose. dunchurch services rugbyWebTheophylline metabolism can be altered by a variety of abnormal physiologic states as well as by exogenous factors. Adult studies demonstrate a significant influence of dietary composition on theophylline biotransformation. ... Compared to the normal diet, high protein diet markedly decreased the half-life, and high carbohydrate diet greatly ... dunchurch service stationWebPurpose: To evaluate prospectively whether serum theophylline concentrations of 25 mg/L and greater were predictable (and presumably preventable) by use of basic pharmacokinetic calculations. Design: Prospective study. Patients: Fifty-five patients with a serum theophylline concentration of at least 25.0 mg/L were evaluated initially and if subsequent … dunchurch rugbyWebNov 3, 2024 · Haemodialysis (if possible charcoal haemoperfusion is the modality of choice). Indications for dialysis include: Theophylline level … dunchurch road works