WebJul 1, 2013 · To the Editor.—We read with interest the article by Turner et al1 regarding the sensitivity and specificity of immunohistochemical staining for the aspartic proteinase Napsin A in the diagnosis of lung adenocarcinoma. It has been well characterized by Turner and others that in addition to granular cytoplasmic staining of 80% to 90% of primary and … WebNov 11, 2010 · Conclusion: Besides electron microscopy identification of inclusions, the light microscopic morphological features together with the biomarker studies highlighting the apical cytoplasmic blush are quite unique and diagnostic of MVID. Furthermore, it is the opinion of the authors that a diagnosis of MVID can be made without electron microscopy.

Usefulness of Succinate dehydrogenase B (SDHB ... - PubMed

WebGross hematuria can result from many disorders, such as primary glomerulopathies, urinary tract infection, ruptured renal cysts, nephrolithiasis, genitourinary malignancies, and … Webexpression (50% cytoplasmic blush). A final diagnosis of gallbladder carcinoma, Stage IVB (pT3NxM1) was made, considering only the para-aortic lymph nodes. The post-operative period was uneventful, and she was started on a gemcitabine-based palliative chemotherapy regimen. DISCUSSION Metastatic neoplasms involving the ovary are diamondback firearms cocoa fl

Role of special stains in diagnostic liver pathology

WebTwo ATM-stained medullary carcinoma cores exhibited cytoplasmic blush staining. Although ATM has primarily been considered a nuclear protein, cytoplasmic reactivity of the ATM (Y170) assay was documented in 9.2% of the ATM-stained normal tissue cores across 35 tissue categories and 3.1% of the assessable ATM-stained cores from the … Webboth cytoplasmic and nuclear compartments of these 18 tumors (Figure 1A-F). One MCPyV-negative case (case 8) showed diffuse but weak cytoplasmic blush (Figure 1G-I). No statistically significant difference was found between primary and metastatic tumors, or based on MCPyV status. The one case with weak p16 staining did not show 9p21 loss … WebEpithelial membrane antigen (EMA) is positive in 80% of meningiomas. The results of S-100 staining are quite variable. Meningiomas also express markers for fibroblasts (i.e., vimentin) and epithelial cells (i.e., EMA and cytokeratins). Antileu 7, an antibody positive in schwannomas, is uniformly negative in meningiomas. circle of life necklaces